<p>Breath of the post-infection T-cell response as measured by IFNγ ELISpot, as quantified by the number of reactive 15-mers, for the vaccine (grey) and placebo (black) groups. The distribution of breadth is shown for all proteins in aggregate; for Gag, Pol, and Nef combined; for other non-insert proteins; and for Gag, Pol, and Nef individually. The p-values refer to tests comparing breadth between vaccine and placebo groups.</p
Magnitude of IFN-γ ELISPOT response (SFC/106 PBMC) and responder rate (%)at one week post last vacci...
<p>Bars are the mean percentages (+SE) of CD8<sup>+</sup> T cells in paired pre- and post-vaccine sa...
The mean values of the total responses (Env, Gag and Pol) are shown. A) Frequency of Env-specific CD...
<p>Pre- and post-infection T-cell responses to individual 15-mers in Gag, Pol, and Nef as measured b...
<p>Magnitude of the post-infection CD8+ T-cell response measured by ICS, as quantified by the percen...
<p>We determined the breadth of T-cell responses in each animal by adding the number of positive IFN...
<p>CD4+ and CD8+ background-adjusted T-cell responses as determined by intracellular cytokine staini...
<p>Average magnitude-breadth (MB) curves in the TZM-bl assay at peak immunogenicity (2 weeks post la...
<p>The y-axis shows the magnitude of CD4+ and CD8+T-cells on a half-log scale across groups A-D for ...
<p>(A) To evaluate T cell response breadth, PBMC from different patient groups were stimulated with ...
<p>Maximal PPD-specific PBMC IFN-γ responses post-vaccination and maximal rAg85A-specific IFN-γ resp...
<div><p>Systems biology is an approach to comprehensively study complex interactions within a biolog...
For each group of donors, the response size shown for each antigen represents the sum of all individ...
<p>Locations of the signature sites and pre- and post-infection T-cell responses for Gag, Nef, and P...
The mean values of the total responses (Env, Gag and Pol) are shown. A) Frequency of Env-specific CD...
Magnitude of IFN-γ ELISPOT response (SFC/106 PBMC) and responder rate (%)at one week post last vacci...
<p>Bars are the mean percentages (+SE) of CD8<sup>+</sup> T cells in paired pre- and post-vaccine sa...
The mean values of the total responses (Env, Gag and Pol) are shown. A) Frequency of Env-specific CD...
<p>Pre- and post-infection T-cell responses to individual 15-mers in Gag, Pol, and Nef as measured b...
<p>Magnitude of the post-infection CD8+ T-cell response measured by ICS, as quantified by the percen...
<p>We determined the breadth of T-cell responses in each animal by adding the number of positive IFN...
<p>CD4+ and CD8+ background-adjusted T-cell responses as determined by intracellular cytokine staini...
<p>Average magnitude-breadth (MB) curves in the TZM-bl assay at peak immunogenicity (2 weeks post la...
<p>The y-axis shows the magnitude of CD4+ and CD8+T-cells on a half-log scale across groups A-D for ...
<p>(A) To evaluate T cell response breadth, PBMC from different patient groups were stimulated with ...
<p>Maximal PPD-specific PBMC IFN-γ responses post-vaccination and maximal rAg85A-specific IFN-γ resp...
<div><p>Systems biology is an approach to comprehensively study complex interactions within a biolog...
For each group of donors, the response size shown for each antigen represents the sum of all individ...
<p>Locations of the signature sites and pre- and post-infection T-cell responses for Gag, Nef, and P...
The mean values of the total responses (Env, Gag and Pol) are shown. A) Frequency of Env-specific CD...
Magnitude of IFN-γ ELISPOT response (SFC/106 PBMC) and responder rate (%)at one week post last vacci...
<p>Bars are the mean percentages (+SE) of CD8<sup>+</sup> T cells in paired pre- and post-vaccine sa...
The mean values of the total responses (Env, Gag and Pol) are shown. A) Frequency of Env-specific CD...