Differential methylation between disease phenotypes in AECs or PBMCs.

<p>Volcano plots of CpG sites interrogated with red and blue points indicating significantly over- and under-methylated sites. Q-values are shown on the y-axis (−log₁₀) and z-score difference on the x-axis (log₂). Dashed lines indicate cut-offs for significance. Within AECs, differences in DNA methylation were assessed in healthy subjects compared to atopics (A) and asthmatics (B) as well as atopic subjects compared to asthmatics (C). The same comparisons were performed in PBMCs (D, E, and F).