<p>Mean number of mutations by treatment, with error bars giving +/−1 SE. In the “scfm+mucin+Cip” treatment, the filled circle represents all evolved genotypes, and the filled diamond represents the ten non-mutator genotypes.</p
<p>A, Genes are in descending order according to the number of variants. B, Genes are in ascending o...
Final fitness value after 20000 generations for each operator (line colour), as a function of the mu...
<p>Total variants detected and number of variants per allele number at that locus.</p
<p>Dark grey are populations evolved in the benign environment and light grey are the populations ev...
<p>The dark gray bars (left) represent the mean final fitness of populations that evolve under each ...
<p>A) Plotted on the x-axis is the observed number of coding sequence (CDS) mutations in each of the...
<p>Drawn is the distribution of the numbers of mutations we would expect to find in 1000 simulated e...
Mutation burden was determined by dividing the total number of mutations in each cell line and divid...
<p><b>A</b>. Absolute abundance (in numbers) of the 70R mutation. <b>B</b>. Relative abundance of th...
<p>For each human gene, the expected number of mutations is obtained based on the normal mutation pa...
<p>(A) Mutations identified in MUC1 to MUC6 clones isolated from M1 to M6 populations (evolved for 4...
Mutations identified using next generation sequencing as stratified by the European society of medic...
<p>The number of mutations was calculated in each of 26 pairs, and its distribution is shown in ST1 ...
<p>Colony number and mutation rate obtained by error-prone PCR mediated mutagenesis.</p
<p><sup>1</sup>b, Mutations only found in isolate b compared to isolate a; c, mutations only found i...
<p>A, Genes are in descending order according to the number of variants. B, Genes are in ascending o...
Final fitness value after 20000 generations for each operator (line colour), as a function of the mu...
<p>Total variants detected and number of variants per allele number at that locus.</p
<p>Dark grey are populations evolved in the benign environment and light grey are the populations ev...
<p>The dark gray bars (left) represent the mean final fitness of populations that evolve under each ...
<p>A) Plotted on the x-axis is the observed number of coding sequence (CDS) mutations in each of the...
<p>Drawn is the distribution of the numbers of mutations we would expect to find in 1000 simulated e...
Mutation burden was determined by dividing the total number of mutations in each cell line and divid...
<p><b>A</b>. Absolute abundance (in numbers) of the 70R mutation. <b>B</b>. Relative abundance of th...
<p>For each human gene, the expected number of mutations is obtained based on the normal mutation pa...
<p>(A) Mutations identified in MUC1 to MUC6 clones isolated from M1 to M6 populations (evolved for 4...
Mutations identified using next generation sequencing as stratified by the European society of medic...
<p>The number of mutations was calculated in each of 26 pairs, and its distribution is shown in ST1 ...
<p>Colony number and mutation rate obtained by error-prone PCR mediated mutagenesis.</p
<p><sup>1</sup>b, Mutations only found in isolate b compared to isolate a; c, mutations only found i...
<p>A, Genes are in descending order according to the number of variants. B, Genes are in ascending o...
Final fitness value after 20000 generations for each operator (line colour), as a function of the mu...
<p>Total variants detected and number of variants per allele number at that locus.</p