No amyloid plaques were detected in transgenic mice using immunohistochemistry.

<p>Immunohistochemical staining of β-amyloid plaques using A) anti-Aβ (1–42) polyclonal antibody B) congo-red staining on cerebral sections of aging (10 month old) wild-type (WT, n = 3), ApoB-100 transgenic (TG, n = 3), and AD model (APPSwe×PSEN1dE9) mice (n = 3). Nuclei were stained using hematoxylin stain. Arrows indicate stained amyloid plaques. Scale bars represent 100 µm (A) and 200 µm (B).