Dioxin and control lineage F1 and F3 generation pubertal abnormality and ovarian disease.

<p>Percentages of females (panel A) and males (panel B) with pubertal abnormality, or primordial follicle loss (panel C), or polycystic ovary disease (panel D), or those with tumor development (panels E and F). The number of diseased rats/total number of rats in each lineage are presented (*P<0.05; ***P<0.001).