Effects of inhibitors and mimics for miR-200 family and miR-182 family miRNAs on OGD-induced cell death in SHSY5Y.

<p>(A) SHSY5Y cells were transfected with either inhibitors or mimics as indicated and 2days later the cell viability was measured by WST-1. Viability was expressed as percentage of negative control for either inhibitor or mimic transfected cells. (B) SHSY5Y cells transfected as mentioned above, and 2days later these cells were subjected to OGD (16 h), and viable cells were measured by WST-1. Viability was expressed as percentage of negative control cells (negative control inhibitor or negative control mimic transfected and not subjected to OGD). In both A and B, inhibitor transfected cells were shown in blue, and mimic transfected cells were shown in red. Data are shown as the mean±SD of three independent experiments. **p<0.01, *p<0.05 compared to control.