Separate comparison of gene expression post-treatment versus gene expression pre-treatment for responding and non-responding patients. Ingenuity pathway analysis suggests differences in regulation of T-cell (<b>Figure 3A</b>) and B-cell (<b>Figure 3B</b>) receptor signaling.

<p>Most of the molecules in the B-cell as well as in the T-cell receptor pathway are down-regulated for non-responding patients upon immunotherapy (POST PRE). Red: up-regulation, Green: down-regulation.