Clustering of gene expression profiles of E2 and vehicle treatment groups at different time points.

<p>The colored cells show the mean expression level of the biological replicates at each time point (1 dpf and 2 dpf: n=3; 3 dpf and 4 dpf: n=4). Red cells represent up-regulated genes, blue cells represent down-regulated genes and black cells represent unchanged expression levels between E2 and vehicle treated groups (<i>P</i><0.005).