GWAS plots for the IAR phenotype displaying results for the 52,583 SNPs that passed quality control.

<p>(A) standard chi-square based association test without permutations; (B) standard association test after 10,000 t-max permutations, and (C) mixed-model test. The SNPs are plotted according to their position on each chromosome (x-axis) and association with the IAR phenotype (y-axis). Significance is given as the −log₁₀ of the uncorrected (A and C) or corrected (B) <i>P</i>-value. The genome-wide significance threshold is log₁₀<i>P</i>>5 or log₁₀<i>EMP2</i>>1. 5.