<p>(A, B) Wild-type cells with an extended pattern of centrin. (C) Approximately 41% of <i>bld2-5</i> cells have centrin that collapses on the nucleus (n = 70). (D) <i>bld2-5</i> cells with a wild-type centrin pattern. (E, F) The rescued transformant, <i>bld2-5</i>; <i>BLD2</i>, and (G, H) the pseudorevertants, <i>bld2-7</i> and (I, J) <i>bld2-9</i> have extended centrin. (K, L) All <i>bld2-6 cells</i> show centrin collapses on or around the nucleus. Scale bar in panel L equals 10 µm. Panels A–L are at the same magnification.</p
Centrioles were labeled by anti-centrin antibody. Insets show magnified images of centrioles. Bar, 1...
AbstractBackground: Centrosomes are the favored microtubule-organizing framework of eukaryotic cells...
<p>(<b>A</b>) Representative panel of GFP-CENP-W cells transfected with siCENP-W for 48 h, stained f...
<p><b>A</b>: Effects on the duplication and segregation of basal bodies, kinetoplasts and nuclei in ...
<div><p><b>A</b>. Immunoblot shows the expression level of centrin2 in cells of the indicated genoty...
SummaryBackgroundCiliary or flagellar basal bodies and centrioles share the same architecture and re...
<p>Asynchronous U2OS-HA-CDC25B cells were incubated in the continued presence (+tet) or absence (-te...
First discovered in unicellular eukaryotes, centrins play crucial roles in basal body duplication an...
<div><p><b>A</b>. Clonogenic survival of cells of the indicated genotype after exposure to the indic...
<p>Histogram shows the mean % <u>+</u> s.d. of cPOC5-GFP-transfected cells of the indicated genotype...
Centrin2 is a centrosomal calcium-binding protein that plays a critical role in centriole dynamics a...
<p>(A–C) IFT74 and katanin p80 do not colocalize. (D–F) IFT74 (green) localizes to the base of the f...
AbstractCentrins are members of the family of Ca2+-binding EF-hand proteins. In photoreceptor cells,...
The principal microtubule-organising centre in animal cells, the centrosome, contains centrin, a sma...
Centrins are calcium-binding proteins associated with microtubules organizing centers. Members of tw...
Centrioles were labeled by anti-centrin antibody. Insets show magnified images of centrioles. Bar, 1...
AbstractBackground: Centrosomes are the favored microtubule-organizing framework of eukaryotic cells...
<p>(<b>A</b>) Representative panel of GFP-CENP-W cells transfected with siCENP-W for 48 h, stained f...
<p><b>A</b>: Effects on the duplication and segregation of basal bodies, kinetoplasts and nuclei in ...
<div><p><b>A</b>. Immunoblot shows the expression level of centrin2 in cells of the indicated genoty...
SummaryBackgroundCiliary or flagellar basal bodies and centrioles share the same architecture and re...
<p>Asynchronous U2OS-HA-CDC25B cells were incubated in the continued presence (+tet) or absence (-te...
First discovered in unicellular eukaryotes, centrins play crucial roles in basal body duplication an...
<div><p><b>A</b>. Clonogenic survival of cells of the indicated genotype after exposure to the indic...
<p>Histogram shows the mean % <u>+</u> s.d. of cPOC5-GFP-transfected cells of the indicated genotype...
Centrin2 is a centrosomal calcium-binding protein that plays a critical role in centriole dynamics a...
<p>(A–C) IFT74 and katanin p80 do not colocalize. (D–F) IFT74 (green) localizes to the base of the f...
AbstractCentrins are members of the family of Ca2+-binding EF-hand proteins. In photoreceptor cells,...
The principal microtubule-organising centre in animal cells, the centrosome, contains centrin, a sma...
Centrins are calcium-binding proteins associated with microtubules organizing centers. Members of tw...
Centrioles were labeled by anti-centrin antibody. Insets show magnified images of centrioles. Bar, 1...
AbstractBackground: Centrosomes are the favored microtubule-organizing framework of eukaryotic cells...
<p>(<b>A</b>) Representative panel of GFP-CENP-W cells transfected with siCENP-W for 48 h, stained f...