<p>Pathological Abnormalities in the Prostates of Targeted <i>Pten</i> Knockout mice.</p
PTEN mutations are among the most frequent genetic alterations found in human prostate cancers. Our ...
<p>(A) Immunostaining of dorsolateral prostate lobes of animals from the 56-week old group of differ...
Prostate cancer is among the commonest cancers in men with high mortality. It is thought to arise fr...
BACKGROUND: Pten functionally acts as a tumor suppressor gene. Lately, tissue-specific ablation of P...
<div><p>(A) Ki-67 staining of AP lobe sections illustrates increasing proliferation with ...
<p><i>Pten</i><sup>+/−</sup> mice develop hyperplasia, dysplasia, and low-grade PIN. <i>...
Knowledge gained from the identification of genetic and epigenetic alterations that contribute to th...
PTEN deficiency predisposes to a subset of human cancers, but the mechanism that underlies such sele...
<p>The numbers of mice displaying the indicated lesions relative to the number of mice analyzed is s...
<p>(A) brightfield images of mouse prostates with epithelial <i>Pten</i> deletion and stabilized β-C...
Evidence linking prostatitis and prostate cancer development is contradictory. To study this link, t...
Gene expression and functional studies have indicated that the molecular programmes involved in pros...
Gene expression and functional studies have indicated that the molecular programmes in-volved in pro...
<p>Representative H&E stain of sections cut from the anterior (AP), ventral (VP) and dorsolateral (D...
Recent studies have shown that several loss-of-function mouse models of prostate carcinogenesis can ...
PTEN mutations are among the most frequent genetic alterations found in human prostate cancers. Our ...
<p>(A) Immunostaining of dorsolateral prostate lobes of animals from the 56-week old group of differ...
Prostate cancer is among the commonest cancers in men with high mortality. It is thought to arise fr...
BACKGROUND: Pten functionally acts as a tumor suppressor gene. Lately, tissue-specific ablation of P...
<div><p>(A) Ki-67 staining of AP lobe sections illustrates increasing proliferation with ...
<p><i>Pten</i><sup>+/−</sup> mice develop hyperplasia, dysplasia, and low-grade PIN. <i>...
Knowledge gained from the identification of genetic and epigenetic alterations that contribute to th...
PTEN deficiency predisposes to a subset of human cancers, but the mechanism that underlies such sele...
<p>The numbers of mice displaying the indicated lesions relative to the number of mice analyzed is s...
<p>(A) brightfield images of mouse prostates with epithelial <i>Pten</i> deletion and stabilized β-C...
Evidence linking prostatitis and prostate cancer development is contradictory. To study this link, t...
Gene expression and functional studies have indicated that the molecular programmes involved in pros...
Gene expression and functional studies have indicated that the molecular programmes in-volved in pro...
<p>Representative H&E stain of sections cut from the anterior (AP), ventral (VP) and dorsolateral (D...
Recent studies have shown that several loss-of-function mouse models of prostate carcinogenesis can ...
PTEN mutations are among the most frequent genetic alterations found in human prostate cancers. Our ...
<p>(A) Immunostaining of dorsolateral prostate lobes of animals from the 56-week old group of differ...
Prostate cancer is among the commonest cancers in men with high mortality. It is thought to arise fr...
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