<p>The numbers of mice displaying the indicated lesions relative to the number of mice analyzed is shown. The values in parentheses correspond to the average number of lesions per prostate where a significant increase in mPIN was observed in A5/<i>Pten</i><sup>+/-</sup> compared to <i>Pten</i><sup>+/-</sup> at 28 weeks.</p>a<p><i>p</i>≤0.05.</p>b<p>Numbers of lesions per animal ranged from 0–17<i><sup>b</sup> p</i> = 0.15.</p
<p><b>A.</b> Representative anterior lobe (AP) histology of <i>Nkx3</i>.<i>1</i><sup><i>-/-</i></sup...
Objectives: Mouse models of prostate cancer are used to test the contribution of individual genes to...
<p><i>Pten</i><sup>+/−</sup> mice develop hyperplasia, dysplasia, and low-grade PIN. <i>...
<p>To determine the development of mPIN lesions over time without hormone treatment, 10-month-old un...
<p>Pathological Abnormalities in the Prostates of Targeted <i>Pten</i> Knockout mice.</p
Evidence linking prostatitis and prostate cancer development is contradictory. To study this link, t...
<p>H&E stained sections are shown for the six indicated genotypes, taken from mice at the following ...
<div><p>(A) Ki-67 staining of AP lobe sections illustrates increasing proliferation with ...
In this report, we describe the development of a transgenic mouse in which a rat probasin promoter (...
In this report, we describe the development of a transgenic mouse in which a rat probasin promoter (...
Genetically modified rodent models provide a platform to dissect the complex and multifactorial mech...
Recent studies have shown that several loss-of-function mouse models of prostate carcinogenesis can ...
<p>Histopathological analysis (most common lesion) of individual prostate lobes in 8-, 12-, 16-, and...
Abstract: Animal models of prostate cancer have been limited in number and in relevance to the human...
The Pathological Classification of Prostate Lesions in Genetically Engineered Mice (GEM) is the resu...
<p><b>A.</b> Representative anterior lobe (AP) histology of <i>Nkx3</i>.<i>1</i><sup><i>-/-</i></sup...
Objectives: Mouse models of prostate cancer are used to test the contribution of individual genes to...
<p><i>Pten</i><sup>+/−</sup> mice develop hyperplasia, dysplasia, and low-grade PIN. <i>...
<p>To determine the development of mPIN lesions over time without hormone treatment, 10-month-old un...
<p>Pathological Abnormalities in the Prostates of Targeted <i>Pten</i> Knockout mice.</p
Evidence linking prostatitis and prostate cancer development is contradictory. To study this link, t...
<p>H&E stained sections are shown for the six indicated genotypes, taken from mice at the following ...
<div><p>(A) Ki-67 staining of AP lobe sections illustrates increasing proliferation with ...
In this report, we describe the development of a transgenic mouse in which a rat probasin promoter (...
In this report, we describe the development of a transgenic mouse in which a rat probasin promoter (...
Genetically modified rodent models provide a platform to dissect the complex and multifactorial mech...
Recent studies have shown that several loss-of-function mouse models of prostate carcinogenesis can ...
<p>Histopathological analysis (most common lesion) of individual prostate lobes in 8-, 12-, 16-, and...
Abstract: Animal models of prostate cancer have been limited in number and in relevance to the human...
The Pathological Classification of Prostate Lesions in Genetically Engineered Mice (GEM) is the resu...
<p><b>A.</b> Representative anterior lobe (AP) histology of <i>Nkx3</i>.<i>1</i><sup><i>-/-</i></sup...
Objectives: Mouse models of prostate cancer are used to test the contribution of individual genes to...
<p><i>Pten</i><sup>+/−</sup> mice develop hyperplasia, dysplasia, and low-grade PIN. <i>...