Modulation of mRNAs as evaluated by microarrays.

<p>Hierarchical clustering and color heat-map of the transcriptome (mRNAs) of thymocytes isolated from 28-day-old DBA-1/J and DBA-2/J mice and CD3⁺ T cells from the spleen and lymph nodes of 4-week-old mice from both strains based on microarray expression profiling. The dendrogram and heat-map were obtained using cluster and tree-view algorithms through Agilent GeneSpring platform. This figure shows the modulation of genes related to immune system based on Gene Ontology (GO terms). Heat map legend: Red = up regulation, green = down regulation, black = unmodulated (Pearson correlation metrics). Sample dendrogram legend: red-line = Naïve T cell DBA-1/J; blue-line = Naïve T cell DBA-2/J; brown-line = Thymocytes DBA-1/J; gray-line = Thymocytes DBA-2/J.