MicroRNA-210 expression is induced in hypoxic fibroblasts but not in hypoxic JEG3 cells; RNA and protein expression of COX10 and ISCU 1/2 are downregulated in both fibroblasts and JEG3 cells cultured in hypoxic condition (1% O₂). <i>A, B)</i>

<p>MiR-210 expression in <b><i>A)</i></b> fibroblasts and in <b><i>B)</i></b> JEG3. <b><i>C, D)</i></b> Transcript levels of COX10 and ISCU1/2 in <b><i>C)</i></b> fibroblasts and <i>D)</i> JEG3. <b><i>E, F)</i></b> Protein levels of COX10 and ISCU1/2 in <b><i>E)</i></b> fibroblasts and in <b><i>F)</i></b> JEG3. * p<0.05, ** p<0.01, *** p<0.001 compared with cells cultured at 21% O2; † p<0.05 compared with cells cultured at 10% O2. Minimum of three biological replicates per cell type for each condition were performed.