Strain NMB-CDC associates with and invades epithelial cell lines at greater rates than strain MC58.
- Stephanie N. Bartley (280045)
- Yih-Ling Tzeng (280046)
- Kathryn Heel (280047)
- Chiang W. Lee (280048)
- Shakeel Mowlaboccus (280049)
- Torsten Seemann (85973)
- Wei Lu (3580)
- Ya-Hsun Lin (280050)
- Catherine S. Ryan (280051)
- Christopher Peacock (280052)
- David S. Stephens (204181)
- John K. Davies (85976)
- Charlene M. Kahler (280053)
Publication date
February 2013
DOIAbstract
<p>The rates of association and invasion of strains NMB-CDC and MC58 into Detroit 562 epithelial cells (Panel A) and human bronchial epithelial cells 16HBE14σ- (Panel B) were assessed. Attachment as percent of the inoculum (black bars read off the left y-axis) and invasion as the percentage of the associated bacteria (white bars read off the right y-axis) is shown. The average rate (+/–SEM) from three biological repeats in triplicate following 6 hrs co-incubation is shown. *: <i>p</i><0.001 determined by Mann-Whitney t-test compared to strain NMB-CDC, ND: Not Detected, viable counts were below the limit of detection.</p
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