HCGβ promotes cell migration and invasion.

<p>(A) We seeded 1×10⁵ cells in a 24-well plate with cell inserts, the cells were added with/without PD98059(25 µM) for 6 h to detect cell migration, the results showed that hCGβ promotes cell migration significantly versus control. (B) In the same conditions we incubated the cells in the invasion chamber with artificial basement membrane, the cells were added with/without PD98059(25 µM) for 12 h to detect cell invasion, the results showed that hCGβ promotes cell invasion significantly. All procedures were performed as described in Methods. *, indicates <i>P<0.05</i> versus control. Data were shown as means ± SEM from three separate tests.