H&E stained lung tissue collected from a prairie dog that died due to MPXV infection (PD8021).

<p><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0055488#pone-0055488-g008" target="_blank">Figure 8a</a> shows a low magnification photomicrograph of the lung (100× original magnification, scale bar = 100 micrometer). The pleural surface (arrows) is covered with an inflammatory exudate admixed with fibrin. Underneath there is a dense inflammatory infiltrate filling the alveoli and expanding alveolar walls. In the center of the image there is a foreign body type giant cell (FB). <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0055488#pone-0055488-g008" target="_blank">Figure 8b</a> shows a high magnification photomicrograph of the foreign body giant cell (FB) in the infiltrate in the lung (400× original magnification, scale bar = 20 micrometer).