Comparison of experimental and simulated matrices.

<p>(<i>A</i>) CRM images of 2, 3, and 4 mg/mL collagen gels, from top to bottom (originally shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0052509#pone.0052509-Harjanto1" target="_blank">[17]</a>); and (<i>B</i>) cross-sections of simulated matrices containing 1200, 2000, and 3000 fibers per lattice, from top to bottom. The CRM images show a view of a whole stack of acquired images from above, while the images from the model depict cross-sections of the matrices, which may give the appearance of there being a significant difference in fiber density between the two.