Norepinephrine Transporter (NET) striatal protein expression and function in 6-OHDA lesioned rats at >70% TH protein loss. A

<p>. NET protein expression. Quantification of NET showed that NET was significantly increased in lesioned striatum compared to its matched non-lesioned control. Statsitics: NET, *<i>p</i><.05, t = 3.251, n = 4 paired observations. <b>B</b>. Representative western blot of NET expression. Relative expression of NET (∼80 kDa band) between contralateral, control, striatum (<b>C</b>) and 6-OHDA-lesioned striatum (<b>L</b>). <b>C</b>. Increased NET function in 6-OHDA lesioned striatum. Desipramine (DMI)-mediated inhibition of [³H] NE uptake between contralateral (control) and lesioned striatum (mean TH loss = 66%). Statistics <i>p</i><0.05, t = 3.127, <i>n</i> = 3 observations.