CD11c-Cre mediated recombination to activate YFP expression in spleen cells after GM-CSF administration in mice.

<p>Mice bearing both CD11c⁻Cre and Rosa26 loxP-STOP-loxP were injected with GM-CSF followed by flow cytometric analysis of their spleen cells for YFP expression in <b>A</b>) different lineages including DCs, myeloid cells, B- and T-lymphocytes, and in <b>B</b>) DC subsets including CD8⁺ DCs, CD8⁻CD11b⁺ DCs and pDCs. <b>C</b>) Analysis of YFP expression in CD11b⁺ DCs during their maturation from group I to group IV.