LPM in cognitively impaired and cognitively preserved patients with MS.

<p>T2-weighted lesion probability maps in cognitively impaired (upper panel, n = 36) and cognitively preserved (lower panel, n = 106) patients with MS. The color overlay created on top of the Montreal Neurological Institute standard brain shows the probability of each voxel containing a lesion in each patient group. The color bar denotes the probability range. The maximum local probability for lesions was higher in cognitively impaired patients (61% peak probability in the forceps major) than in cognitively preserved patients (37% peak probability in the posterior corona radiata). Images are shown in radiological convention.