Expression of pro-inflammatory mediators in kidneys infected by UPEC.

<p>Expression of MIP-2, KC, IL-1ß, IL-6, MCP-1, RANTES and TNF-α in the day 2 and day 7 post-infection kidneys following the transurethral inoculation of the CFT073 and TN03 UPEC isolates. mRNA expression of each inflammatory marker was calculated using the −ΔΔCT method. Values are expressed as the relative fold increase in kidneys of each mRNA level of proinflammatory mediator in comparison with that measured in naive mice. Horizontal bars represent the median values. Statistical differences between the strains were determined at each time point using the Kruskal-Wallis equality-of-populations rank test.