Hydrocephalus in JAM-C^−/− C57BL/6 mice develops over time. A:

<p>Different stages in hydrocephalus severity of JAM-C^−/− C57BL/6 mice are shown with their assigned scores. <b>B:</b> Seven male JAM-C^−/− C57BL/6 mice were scored weekly for changes in hydrocephalus severity. On average, first hydrocephalus symptoms appeared around 1 month after birth. Score 2 was reached about 2 weeks later. Finally, score 3 developed in most mice within the following week.