<p> In comparison to age-matched C57BL/6 wildtype littermates JAM-C<sup>−/−</sup> C57BL/6 mice are often smaller and display a hydrocephalus. <b>B</b> Histological analysis of hemalaun-stained brain cryosections reveals greatly enlarged lateral ventricles (arrows), a strikingly thinned cortex and overall alteration of brain anatomy in JAM-C<sup>−/−</sup> C57BL/6 mice.</p
<p>Double-transgenic Ro1 mice and age-matched littermate controls were taken off dox at P30 and anal...
<p><b>(A, B)</b> Unlike <i>Zmynd10</i><sup><i>+/+</i></sup> mice (A), <i>Zmynd10</i><sup><i>−/−</i><...
<p>Lateral ventricles (right and left ventricles) volume is significantly larger (**<i>p</i><0.01) i...
<p>Immunostaining for neurofilament (NF) together with Tuj1 reveals loss of cortical layering in JAM...
<p>Different stages in hydrocephalus severity of JAM-C<sup>−/−</sup> C57BL/6 mice are shown with the...
<p>The progression of hydrocephalus in mice maintained off dox throughout gestation and development ...
<p>JAM-C+/− mice were interbread and offspring was genotyped at postnatal day 21. Abbreviations: f =...
<p><b>A:</b> Hematoxylin and eosin staining showing signs of fresh (asterisk) and elder (arrows) ble...
<p>38 JAM-C<sup>−/−</sup> C57BL/6 mice (21 females and 17 males) and 40 JAM-C<sup>−/−/</sup>/Tie-2 J...
<p>Immunostaining for glial fibrillary acidic protein (GFAP) reveals reactive gliosis in JAM-C<sup>−...
The junctional adhesion molecule (JAM)-C is a widely expressed adhesion molecule regulating cell adh...
The junctional adhesion molecule (JAM)-C is a widely expressed adhesion molecule regulating cell adh...
<p>(A) H&E staining. The left panels are representative slides from a control mouse at 4 weeks of ag...
<p><b>A,B:</b> H&E stained coronal section of adult <i>Sox3</i> transgenic mouse brain without (A) a...
Hydrocephalus is a common neurological problem in humans, Usually caused by an impairment of cerebro...
<p>Double-transgenic Ro1 mice and age-matched littermate controls were taken off dox at P30 and anal...
<p><b>(A, B)</b> Unlike <i>Zmynd10</i><sup><i>+/+</i></sup> mice (A), <i>Zmynd10</i><sup><i>−/−</i><...
<p>Lateral ventricles (right and left ventricles) volume is significantly larger (**<i>p</i><0.01) i...
<p>Immunostaining for neurofilament (NF) together with Tuj1 reveals loss of cortical layering in JAM...
<p>Different stages in hydrocephalus severity of JAM-C<sup>−/−</sup> C57BL/6 mice are shown with the...
<p>The progression of hydrocephalus in mice maintained off dox throughout gestation and development ...
<p>JAM-C+/− mice were interbread and offspring was genotyped at postnatal day 21. Abbreviations: f =...
<p><b>A:</b> Hematoxylin and eosin staining showing signs of fresh (asterisk) and elder (arrows) ble...
<p>38 JAM-C<sup>−/−</sup> C57BL/6 mice (21 females and 17 males) and 40 JAM-C<sup>−/−/</sup>/Tie-2 J...
<p>Immunostaining for glial fibrillary acidic protein (GFAP) reveals reactive gliosis in JAM-C<sup>−...
The junctional adhesion molecule (JAM)-C is a widely expressed adhesion molecule regulating cell adh...
The junctional adhesion molecule (JAM)-C is a widely expressed adhesion molecule regulating cell adh...
<p>(A) H&E staining. The left panels are representative slides from a control mouse at 4 weeks of ag...
<p><b>A,B:</b> H&E stained coronal section of adult <i>Sox3</i> transgenic mouse brain without (A) a...
Hydrocephalus is a common neurological problem in humans, Usually caused by an impairment of cerebro...
<p>Double-transgenic Ro1 mice and age-matched littermate controls were taken off dox at P30 and anal...
<p><b>(A, B)</b> Unlike <i>Zmynd10</i><sup><i>+/+</i></sup> mice (A), <i>Zmynd10</i><sup><i>−/−</i><...
<p>Lateral ventricles (right and left ventricles) volume is significantly larger (**<i>p</i><0.01) i...