Telomere abnormalities distinguished by Rb fusions and interstitial signals in OSA cells.

<p>(A) Four types of telomere abnormalities; ITS¹, one interstitial telomeric sequence, ITS²⁺, more than one interstitial telomeric sequences, Rb¹, Robertsonian translocation with one telomere signal in the centromere region, and Rb²⁺, Robertsonian translocation with more than one telomere signals in the centromere region. Rb⁻ represents Robertsonian translocation with no telomere signal in the centromere region. (B) The number of telomere aberrations per each metaphase cell. Error bars indicate the standard error of the means.