Fungal homologues of voltage-gated K⁺ (K_v) channel subunits.

<p>(<b>A</b>) Predicted topology of fungal K_v channel subunit homologues; (<b>B</b>) Multiple sequence alignment of the putative voltage sensor TMD4 regions of human K_v1.2 and fungal K_v channel homologues. Filled triangles above the alignment indicate the positions of conserved basic residues in K_v1.2; (<b>C</b>) Multiple sequence alignment of the putative pore regions of human K_v1.2 and fungal K_v channel homologues. Predicted pore-lining helices of each protein are underlined and the shaded bar indicates the highly conserved GXG motif within the selectivity filter.