<p>MDMs were stimulated with TLR2/1L (10 µg/ml) for 21 hr. TC supernatants were monitored for the production of (<b>A</b>) chemokine Gro-α and (<b>B</b>) cytokine IL-6 by ELISA. Results are shown after subtraction of background levels of Gro-α or IL-6 monitored in un-stimulated cells. All results are average of at least four independent experiments (MDMs isolated from four to five independent donors each from the Dené and Caucasians participants) ± standard error.</p
<p>Human PBMCs were exposed to IL-6 (10 ng/ml) in combination with sIL-6R (125 ng/ml) (IL-6/sIL-6R) ...
<p>Neutrophils were isolated from WT and CARD9<sup>-/-</sup> mice and co-cultured with H9C2 cells. M...
<p>Each sample was measured in duplicate. The horizontal dashed line is the IL-6 level ten times bac...
<p>BMMØ were stimulated with mAb-iB<sup>TLR2</sup> under the indicated conditions. The level of cell...
<p><u>Panel A:</u> BMMØ were stimulated with mAb-iB<sup>TLR2</sup> under the indicated conditions an...
<p>PBMCs and PBLs were prepared as described in the Materials and Methods, stimulated for 1, 3 or 6-...
<p>The concentrations of (A) IL-6, (B) TNF-α, (C) IL-12 and (D) IL-10 were determined by ELISA assay...
<p>Human PBMCs were pre-exposed to IL-6/sIL-6R for 1 hour. Cells were then stimulated with IL-1β (1 ...
<p>WT, TLR2/9<sup>-/-</sup> and MyD88<sup>-/-</sup> BMDMs were cultured with or without SR (0.05 mg/...
<p>MDMs were stimulated with TLR2/1L (10 µg/ml) in the presence of autologous serum. Gene expression...
<p>Human PBMCs were pre-exposed to IL-6/sIL-6R for 1 hour. Cells were then stimulated with poly(I-C)...
<p>Cells were stimulated for 72 hours with the indicted concentration of peptide and cytokine concen...
<p>gmMφ and mMφ were stimulated with ICs (50 µg/ml) (<b>A</b>), LPS (100 ng/ml) or LPS+ICs (<b>B</b>...
<p>The concentrations of (A) IL-6, (B) TNF-a, (C) IL-12 and (D) IL-10 were determined by ELISA assay...
<p>(A),TNF-α levels were measured by ELISA at 4 h, 8h and24 h; (B), IL-6 levels were measured at 4h,...
<p>Human PBMCs were exposed to IL-6 (10 ng/ml) in combination with sIL-6R (125 ng/ml) (IL-6/sIL-6R) ...
<p>Neutrophils were isolated from WT and CARD9<sup>-/-</sup> mice and co-cultured with H9C2 cells. M...
<p>Each sample was measured in duplicate. The horizontal dashed line is the IL-6 level ten times bac...
<p>BMMØ were stimulated with mAb-iB<sup>TLR2</sup> under the indicated conditions. The level of cell...
<p><u>Panel A:</u> BMMØ were stimulated with mAb-iB<sup>TLR2</sup> under the indicated conditions an...
<p>PBMCs and PBLs were prepared as described in the Materials and Methods, stimulated for 1, 3 or 6-...
<p>The concentrations of (A) IL-6, (B) TNF-α, (C) IL-12 and (D) IL-10 were determined by ELISA assay...
<p>Human PBMCs were pre-exposed to IL-6/sIL-6R for 1 hour. Cells were then stimulated with IL-1β (1 ...
<p>WT, TLR2/9<sup>-/-</sup> and MyD88<sup>-/-</sup> BMDMs were cultured with or without SR (0.05 mg/...
<p>MDMs were stimulated with TLR2/1L (10 µg/ml) in the presence of autologous serum. Gene expression...
<p>Human PBMCs were pre-exposed to IL-6/sIL-6R for 1 hour. Cells were then stimulated with poly(I-C)...
<p>Cells were stimulated for 72 hours with the indicted concentration of peptide and cytokine concen...
<p>gmMφ and mMφ were stimulated with ICs (50 µg/ml) (<b>A</b>), LPS (100 ng/ml) or LPS+ICs (<b>B</b>...
<p>The concentrations of (A) IL-6, (B) TNF-a, (C) IL-12 and (D) IL-10 were determined by ELISA assay...
<p>(A),TNF-α levels were measured by ELISA at 4 h, 8h and24 h; (B), IL-6 levels were measured at 4h,...
<p>Human PBMCs were exposed to IL-6 (10 ng/ml) in combination with sIL-6R (125 ng/ml) (IL-6/sIL-6R) ...
<p>Neutrophils were isolated from WT and CARD9<sup>-/-</sup> mice and co-cultured with H9C2 cells. M...
<p>Each sample was measured in duplicate. The horizontal dashed line is the IL-6 level ten times bac...