Quantile-Quantile plot of the GWAS results.

<p>In this plot, each dot corresponds to a SNP tested for association where the observed –log₁₀ p values, shown by vertical axis, were plotted by the expected –log₁₀ p values under the null hypothesis. Upper right dots with higher observed significance than expected represent candidate variants for association with the phenotype tested (CAD category 1, control subjects; CAD category 2, patients with ≤50% stenosis in any coronary artery; CAD category 3, patients with >50% stenosis in any of the coronary arteries). The genomic control ratio (λ) was 1.033, indicating the lack of strong effect of systematic error such as population stratification.