Nefopam suppresses the neoplastic phenotype in murine aggressive fibromatosis tumors.

<p>The number of tumors found in male <i>Apc1638N</i> mice. Data is given as the mean and 95% confidence intervals for the number of tumors formed in male mice in no treatment; 0.1% DMSO (carrier); or Nefopam treatment groups. Data is given as means and 95% confidence intervals. An asterisk over a data point indicates a significant difference form the control cell cultures. Mice treated with the carrier showed a comparable number of tumors to mice that received no treatment, while mice treated with Nefopam developed significantly fewer tumors.