<p>Western blot analysis of a series of cell cycle related factors showed the protein levels of Cyclin A, B, D1, E and p-Rb were decreased and P27 expression was increased after silencing TRIM24 in H1299 and A549 cells (A). There was no significant change of p53 luciferase activity after siRNA treatment in both cell lines (B).</p
We have analyzed the regulation of subcellular compartmentation of mutant and wild-type (WT) p53 pro...
<p>The percentage of G1 phase was increased in cells with TRIM24 knockdown (H1299 and A549, p<0.05),...
<p>The tumor suppressor protein p53 is central to the cellular stress response and may be a predicti...
<p>H1299 cells transiently transfected with TRIM59 siRNA-1, TRIM59 siRNA-2 or control siRNA were cul...
<p>4(A). Western blotting analysis of the cell-cycle related proteins showed the expression of Cycli...
<p>The indicated cells stably transduced with the pGreenFire reporter construct encoding luciferase ...
Untreated or PTX treated lysates were probed for expression of canonical cell cycle proteins. (A) Re...
<p>Cell cultures A, B and C were cultured in suspension-, growth-, and differentiation medium, and q...
<p>A. Expression levels of TRIM24, p53 and RARα were analyzed by western blot in a panel of lung can...
<p>Inhibition of AP-4 expression could up-regulate the expression of p53 and p21 mRNA and protein, b...
<p>The expression of p53 was analysed by microarray, qPCR and Western blot. (A) IPEC-J2 showed a 27....
Transfedion of wild-type p53 into a pre-B, p53 nonproducer cell line yielded the generation of stabl...
The tumor suppressor p53 is commonly referred to as the guardian of the genome due to its ability ...
The cell division cycle 25 (CDC25) phosphatases regulate key transitions between cell-cycle phases d...
The expression of the cyclin-dependent kinase inhibitor (CDKI) p27 protein was investigated in relat...
We have analyzed the regulation of subcellular compartmentation of mutant and wild-type (WT) p53 pro...
<p>The percentage of G1 phase was increased in cells with TRIM24 knockdown (H1299 and A549, p<0.05),...
<p>The tumor suppressor protein p53 is central to the cellular stress response and may be a predicti...
<p>H1299 cells transiently transfected with TRIM59 siRNA-1, TRIM59 siRNA-2 or control siRNA were cul...
<p>4(A). Western blotting analysis of the cell-cycle related proteins showed the expression of Cycli...
<p>The indicated cells stably transduced with the pGreenFire reporter construct encoding luciferase ...
Untreated or PTX treated lysates were probed for expression of canonical cell cycle proteins. (A) Re...
<p>Cell cultures A, B and C were cultured in suspension-, growth-, and differentiation medium, and q...
<p>A. Expression levels of TRIM24, p53 and RARα were analyzed by western blot in a panel of lung can...
<p>Inhibition of AP-4 expression could up-regulate the expression of p53 and p21 mRNA and protein, b...
<p>The expression of p53 was analysed by microarray, qPCR and Western blot. (A) IPEC-J2 showed a 27....
Transfedion of wild-type p53 into a pre-B, p53 nonproducer cell line yielded the generation of stabl...
The tumor suppressor p53 is commonly referred to as the guardian of the genome due to its ability ...
The cell division cycle 25 (CDC25) phosphatases regulate key transitions between cell-cycle phases d...
The expression of the cyclin-dependent kinase inhibitor (CDKI) p27 protein was investigated in relat...
We have analyzed the regulation of subcellular compartmentation of mutant and wild-type (WT) p53 pro...
<p>The percentage of G1 phase was increased in cells with TRIM24 knockdown (H1299 and A549, p<0.05),...
<p>The tumor suppressor protein p53 is central to the cellular stress response and may be a predicti...