Declined specific IFNγ response by hepatic CD8+ memory T cells over time.

<p>Sporozoite specific IFNγ response by hepatic CD8+CD44hi T cells was measured by intracellular staining at 3 months post-immunization (A) – individual values and median are plotted. Longevity of the specific (sporozoites) and non-specific (PMA/Ionomycin) IFNγ response was further assessed 6 and 9 months after immunization (B) – error bars represent SEM. * = p<0.05, ** = p<0.001.