<p>A: L6 myotubes were incubated with incremental concentrations of CGA for 24 hours. B: L6 myotubes were incubated with 2 mmol/l CGA at different incubation periods up to 24 hours. 2-deoxyglucose uptake was measure over a 30-minute period, using liquid scintillation counter. Readings are expressed as percentage increase over basal uptake of cells incubated with vehicle. <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0032718#s3" target="_blank">Results</a> are the mean ± SE of three independent experiments. *<i>P</i><0.05, **<i>P</i><0.01 compared with vehicle-treated control.</p
<p><b>A.</b> Basal mitochondrial oxygen consumption rate. *, p<0.05, GAL vs HG and LG. <b>B.</b> Sta...
<p>Conditioned media (2% in final media volume) from <b>(a,</b> basal state; <b>b</b> insulin-stimul...
<p>(<b>A</b>) Myotubes cultured in 5 mM glucose (G5) or in 25 mM glucose (G25) for 48 hours were tra...
<p>L6 myotubes were incubated with 2 mmol/l CGA for 24 hours. A: Myotubes were preincubated with 100...
<p>L6 myotubes were transfected with vehicle, unrelated siRNA or AMPKα1/2 siRNA as described in Rese...
<p>Myotubes were incubated with incremental concentrations of CGA for 24 hours. A: Viability of myot...
<p>*p < 0.05, compared with control. **p < 0.05, compared with DBM-treated cells. (B) L6 myotubes we...
<p><b>A.</b> and <b>B.</b> Differentiated myotubes were incubated for 48 h with simvastatin (S) with...
<p>A: Oral glucose tolerance test was performed on db/db mice (n = 4) treated with different treatme...
<p>Sub-confluent cells were incubated in control, CA, HG or CA+HG conditions for 30 min, 3, 6, 24 an...
<p><b>A.</b> Basal oxygen consumption rate. <b>B.</b> State 4 respiration (leak dependent; non-phosp...
<p><b>A.</b> Fusion index was measured in myotubes differentiated in HG (25 mM glucose), LG (5 mM gl...
<p>L6 myotubes were pre-incubated with 10 μmol/L of MYR or SKI II for 2 h [MYR/SKI II + PA (2 h)] an...
<p>Satellite cells were isolated from lean, healthy males (n = 6), differentiated in either high glu...
<p>(<b>A</b>) <b>and oleic acid metabolism</b> (<b>B</b>)<b>.</b> Cultured myotubes were electricall...
<p><b>A.</b> Basal mitochondrial oxygen consumption rate. *, p<0.05, GAL vs HG and LG. <b>B.</b> Sta...
<p>Conditioned media (2% in final media volume) from <b>(a,</b> basal state; <b>b</b> insulin-stimul...
<p>(<b>A</b>) Myotubes cultured in 5 mM glucose (G5) or in 25 mM glucose (G25) for 48 hours were tra...
<p>L6 myotubes were incubated with 2 mmol/l CGA for 24 hours. A: Myotubes were preincubated with 100...
<p>L6 myotubes were transfected with vehicle, unrelated siRNA or AMPKα1/2 siRNA as described in Rese...
<p>Myotubes were incubated with incremental concentrations of CGA for 24 hours. A: Viability of myot...
<p>*p < 0.05, compared with control. **p < 0.05, compared with DBM-treated cells. (B) L6 myotubes we...
<p><b>A.</b> and <b>B.</b> Differentiated myotubes were incubated for 48 h with simvastatin (S) with...
<p>A: Oral glucose tolerance test was performed on db/db mice (n = 4) treated with different treatme...
<p>Sub-confluent cells were incubated in control, CA, HG or CA+HG conditions for 30 min, 3, 6, 24 an...
<p><b>A.</b> Basal oxygen consumption rate. <b>B.</b> State 4 respiration (leak dependent; non-phosp...
<p><b>A.</b> Fusion index was measured in myotubes differentiated in HG (25 mM glucose), LG (5 mM gl...
<p>L6 myotubes were pre-incubated with 10 μmol/L of MYR or SKI II for 2 h [MYR/SKI II + PA (2 h)] an...
<p>Satellite cells were isolated from lean, healthy males (n = 6), differentiated in either high glu...
<p>(<b>A</b>) <b>and oleic acid metabolism</b> (<b>B</b>)<b>.</b> Cultured myotubes were electricall...
<p><b>A.</b> Basal mitochondrial oxygen consumption rate. *, p<0.05, GAL vs HG and LG. <b>B.</b> Sta...
<p>Conditioned media (2% in final media volume) from <b>(a,</b> basal state; <b>b</b> insulin-stimul...
<p>(<b>A</b>) Myotubes cultured in 5 mM glucose (G5) or in 25 mM glucose (G25) for 48 hours were tra...