Alignments of the N-termini of P from <i>Pneumovirinae</i>, <i>Filoviridae</i> and <i>Rhabdoviridae</i>.

<p>Conventions as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0031719#pone-0031719-g002" target="_blank">Figure 2</a>. Abbreviations and accession numbers are in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0031719#pone-0031719-t002" target="_blank">Table 2</a>. (A) Mir motif of <i>Pneumovirinae</i>. A1 – Alignment of the N-terminus of P of both <i>metapneumoviruses</i> and <i>pneumoviruses</i>. A2 – Same alignment as in A1 but restricted to <i>metapneumoviruses</i>. Positions corresponding to soyuz1 are indicated above the alignment. The coloring of sequence conservation is different from A1 since conservation is now based only on the two <i>metapneumovirus</i> sequences. (B) Sputnik motif of <i>Filoviridae</i>. The asterisk indicates the newly published sequence of <i>LLoviu virus</i>. (C) N-termini of the P of two <i>Rhabdoviridae</i> genera: <i>lyssavirus</i> and <i>vesiculovirus</i>. A disputed L-binding site in <i>lyssavirus</i> P is indicated <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0031719#pone.0031719-Chenik1" target="_blank">[108]</a>. The boundaries of the N°-binding region of VSV P were obtained from the crystal structure of N°-P <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0031719#pone.0031719-Leyrat3" target="_blank">[58]</a>.