<p>Relative levels of ROS after treatment with bleomycin are given for murine and human LN9, GM166VA7 and NBS-1LBI cells with the given genotypes and after the indicated treatments. ** p = 0.0095 in the Mann-Whitney U Test (two-tailed, n<sup>1</sup> = 4, n<sup>2</sup> = 6); * p = 0.017 in the Mann-Whitney U Test (two-tailed, n<sup>1</sup> = 3, n<sup>2</sup> = 12).</p
A. Mutation rate in vivo. Fecal pellets from wildtype or ΔmutS mutants colonized in NAC- (blue circl...
<p>(A–C) MDA-MB-231 and MDA-MB-435 cells were incubated with U75302 (1 µM), LY255283 (10 µM), or DMS...
<p>(A) Bone marrow cells freshly harvested from five-month-old <i>Ptpn11<sup>D61G/+</sup></i> and <i...
<p>(A) FACS profiles of ROS measurements in murine cells with the indicated genotypes with or withou...
<p>(A) FACS profiles of ROS measurements in NBS-1LBI patient cells 12 hours after treatment with ble...
<p>Lysates from mouse (A) and human LN9 and GM166VA7 fibroblasts (B) with the given genotypes were h...
<p>WT and NER<sup>-</sup> cells and their isogenic WTρ<sup>°</sup> and NER<sup>-</sup>ρ<sup>0</sup> ...
<p>(A, B) The expression of NNMT in Bcap-37 and MDA-MB-231 cells transfected by siRNAs at a final co...
<p>(A) Bone marrow cells freshly harvested from five-month-old <i>Ptpn11<sup>D61G/+</sup></i> and <i...
<p>(A) F9, F9A353V and F9A353V cells transfected with GSE24.2 (10 µg DNA per million cells). F9A353V...
<p>A, B and C: Western blot analysis on XBP1S and p47phox levels in the cultured MCs before and afte...
<p>(A) Percentage of nuclei with different types of γ-H2AX staining patterns in the flight and groun...
<p>(A) After stimulation with LxB (1,000 nm; 0.06%, 20 nm; 0.02%) ± LPS for 1 h in stirred culture, ...
<p>(A) MNNG increased the intracellular ROS levels in TW01 or NA cells and the ROS scavengers reduce...
<p>Production of ROS was monitored using a DCFH-DA, and average fluorescence intensity of 10,000 cel...
A. Mutation rate in vivo. Fecal pellets from wildtype or ΔmutS mutants colonized in NAC- (blue circl...
<p>(A–C) MDA-MB-231 and MDA-MB-435 cells were incubated with U75302 (1 µM), LY255283 (10 µM), or DMS...
<p>(A) Bone marrow cells freshly harvested from five-month-old <i>Ptpn11<sup>D61G/+</sup></i> and <i...
<p>(A) FACS profiles of ROS measurements in murine cells with the indicated genotypes with or withou...
<p>(A) FACS profiles of ROS measurements in NBS-1LBI patient cells 12 hours after treatment with ble...
<p>Lysates from mouse (A) and human LN9 and GM166VA7 fibroblasts (B) with the given genotypes were h...
<p>WT and NER<sup>-</sup> cells and their isogenic WTρ<sup>°</sup> and NER<sup>-</sup>ρ<sup>0</sup> ...
<p>(A, B) The expression of NNMT in Bcap-37 and MDA-MB-231 cells transfected by siRNAs at a final co...
<p>(A) Bone marrow cells freshly harvested from five-month-old <i>Ptpn11<sup>D61G/+</sup></i> and <i...
<p>(A) F9, F9A353V and F9A353V cells transfected with GSE24.2 (10 µg DNA per million cells). F9A353V...
<p>A, B and C: Western blot analysis on XBP1S and p47phox levels in the cultured MCs before and afte...
<p>(A) Percentage of nuclei with different types of γ-H2AX staining patterns in the flight and groun...
<p>(A) After stimulation with LxB (1,000 nm; 0.06%, 20 nm; 0.02%) ± LPS for 1 h in stirred culture, ...
<p>(A) MNNG increased the intracellular ROS levels in TW01 or NA cells and the ROS scavengers reduce...
<p>Production of ROS was monitored using a DCFH-DA, and average fluorescence intensity of 10,000 cel...
A. Mutation rate in vivo. Fecal pellets from wildtype or ΔmutS mutants colonized in NAC- (blue circl...
<p>(A–C) MDA-MB-231 and MDA-MB-435 cells were incubated with U75302 (1 µM), LY255283 (10 µM), or DMS...
<p>(A) Bone marrow cells freshly harvested from five-month-old <i>Ptpn11<sup>D61G/+</sup></i> and <i...