Plasma PK Characteristics of m-HemaMax in Irradiated and Non-Irradiated Mice.
- Lena A. Basile (331369)
- Dolph Ellefson (331370)
- Zoya Gluzman-Poltorak (331371)
- Katiana Junes-Gill (331372)
- Vernon Mar (331373)
- Sarita Mendonca (331374)
- Joseph D. Miller (331375)
- Jamie Tom (331378)
- Alice Trinh (331380)
- Timothy K. Gallaher (331382)
Publication date
February 2013
DOIAbstract
<p>Animals received m-HemaMax subcutaneously at a dose of 10 ng/mouse, 20 ng/mouse, 40 ng/mouse, or 200 ng/mouse in the absence of irradiation or at 24 hours after an LD<sub>90/30</sub> of TBI. The plasma concentrations of m-HemaMax were determined by ELISA.</p><p>AUC = area under the curve; C<sub>max</sub> = maximum plasma concentrations; NR = no irradiation; R = irradiation; TBI = total body irradiation; T<sub>max</sub> = time to achieve the maximum plasma concentration; t<sub>1/2</sub> = half life.</p
Add to ORKG