Fibrinolytic activity in human neuropathies.

<p>In situ zymography in sural nerve biopsies of patients (#4 and #3) with regenerating (A, B) and (#15 and #18) non-regenerating (C, D) neuropathies. Fluorescent signal as a readout of fibrinolytic activity is very high in regenerating nerves, and very low in non-regenerating nerves. A^I and C^I are the same reaction depicted in A and C in which fibrinolytic reaction was blocked by amiloride (PAstop). Zym = fibrinolytic activity; Nf = neurofilaments. Bar = 50 µm.