Overall asynchronous glutamate release increases with larger synchronous EPSC amplitudes in TRPV1+ but not in TRPV1− afferents.

<p><b>A</b>) Across NTS neurons each additional input from TRPV1+ ST afferents (N = 15 neurons with n = 32 inputs) produced additional asynchronous release proportional to the evoked EPSC1. <b>B</b>. Additive TPRV1− inputs produced no additional asynchronous release (N = 12 neurons with n = 24 inputs). TRPV1+ inputs shown with red symbols and TRPV1− shown with blue symbols. Recruited inputs: 1^st = circle, 2^nd = square, 3^rd = triangle, 4^th = diamond, and 5^th = inverted triangle. Data are fit with a linear regression: TRPV1+ slope = 2.24±0.20, R² = 0.55; and TRPV1− slope = 0.18±0.06, R² = 0.30.