NBC on the apical membrane of rat epididymal epithelium regulates epididymal apical pH.

<p>In the control group, the cultured rat caput epididymal epithelium was immersed in Cl⁻ free KH solution without any treatment of DIDS (n = 7). 1 mM DIDS was applied to the apical(n = 3) or basolateral(n = 3) side of the cultured epithelial monolayer and incubated for 1 hour. Ctl, Control; DIDS, 1 mM DIDS; ap, apical; bl, basolateral; N.S., no significant difference vs Ctl; All bars represent mean ± S.E.M. (*P<0.05 vs Ctl).