<p>Cells were isolated from either challenged only (c) or sensitized and challenged (s/c) <i>Il22</i> deficient and congenic wild-type controls (IL-22<sup>+/+</sup>). Panel A shows a representative plot of intracellular IL-5 and IFN-γ staining. Panel B shows cell counts for IL-4 positive, IFN-γ negative (IL-4<sup>+</sup>IFN<sup>−</sup>), IL-5 positive, IFN-γ negative (IL-5<sup>+</sup>IFN<sup>−</sup>), IFN-γ positive, IL-5 negative (IFN<sup>+</sup>IL-5<sup>−</sup>) and IL-17A positive, IFN-γ negative (IL-17A<sup>+</sup>IFN<sup>−</sup>) cells. Each dot represent a single mouse. Data from 2 independent experiments are given. * p<0.05 compared to all other groups.</p
<p>WT C57BL/6 mice or IL-21R KO mice were infected with 0.1 LD<sub>50</sub> PR8 and lung cell suspen...
The lungs from infected and treated mice were macerated and ex-vivo stimulated with M.tb complete so...
<p>B cell −/− and control mice were chronically challenged with allergen, and cytokine levels were a...
<p>Panel A shows the expression of CD25 and CD44 among IL-22 producing cells. Panel B shows the IFN-...
<p>Panel A: IL-22 intracellular staining in lung cells 24 hrs after inhaled exposure of OT II mice w...
<p>Several signature cytokines in pulmonary ILC (gated as CD45<sup>+</sup>, Lin<sup>-</sup> CD127<su...
Intracellular cytokine staining of lung cells was carried out by Flow cytometry after in vitro stimu...
<p>Experimental mice were infected with approx. 100 CFU <i>Mtb</i> via the aerosol route. (<b>A</b>,...
Intracellular cytokine staining of lung cells was carried out by Flow cytometry after in vitro stimu...
<p>A. IFN-gamma ELISPOT. Splenocytes were collected on day 6 post-infection with mouse-adapted NC/99...
<p>C57BL/6 mice were inoculated with PBS (mock) or infected intranasally with 10<sup>5</sup> PFU inf...
<p>Lungs from infected CD1d<sup>−/−</sup> or C57BL/6 (WT C57) were harvested at 7 (A–C) and 12 d.p.i...
<p>The isolated lung mononuclear cells were detected for IL-9 expression by FACS. (A) Representative...
<p>Mice were sensitized and challenged with OVA as described in the legend for <a href="http://www.p...
<p>C57BL/6 mice (black bars) and IL-22<sup>−/−</sup> (white bars) mice were infected with approx. 10...
<p>WT C57BL/6 mice or IL-21R KO mice were infected with 0.1 LD<sub>50</sub> PR8 and lung cell suspen...
The lungs from infected and treated mice were macerated and ex-vivo stimulated with M.tb complete so...
<p>B cell −/− and control mice were chronically challenged with allergen, and cytokine levels were a...
<p>Panel A shows the expression of CD25 and CD44 among IL-22 producing cells. Panel B shows the IFN-...
<p>Panel A: IL-22 intracellular staining in lung cells 24 hrs after inhaled exposure of OT II mice w...
<p>Several signature cytokines in pulmonary ILC (gated as CD45<sup>+</sup>, Lin<sup>-</sup> CD127<su...
Intracellular cytokine staining of lung cells was carried out by Flow cytometry after in vitro stimu...
<p>Experimental mice were infected with approx. 100 CFU <i>Mtb</i> via the aerosol route. (<b>A</b>,...
Intracellular cytokine staining of lung cells was carried out by Flow cytometry after in vitro stimu...
<p>A. IFN-gamma ELISPOT. Splenocytes were collected on day 6 post-infection with mouse-adapted NC/99...
<p>C57BL/6 mice were inoculated with PBS (mock) or infected intranasally with 10<sup>5</sup> PFU inf...
<p>Lungs from infected CD1d<sup>−/−</sup> or C57BL/6 (WT C57) were harvested at 7 (A–C) and 12 d.p.i...
<p>The isolated lung mononuclear cells were detected for IL-9 expression by FACS. (A) Representative...
<p>Mice were sensitized and challenged with OVA as described in the legend for <a href="http://www.p...
<p>C57BL/6 mice (black bars) and IL-22<sup>−/−</sup> (white bars) mice were infected with approx. 10...
<p>WT C57BL/6 mice or IL-21R KO mice were infected with 0.1 LD<sub>50</sub> PR8 and lung cell suspen...
The lungs from infected and treated mice were macerated and ex-vivo stimulated with M.tb complete so...
<p>B cell −/− and control mice were chronically challenged with allergen, and cytokine levels were a...