<p>Using Simple PCI software analysis of images captured by confocal microscopy, the mean fluorescent intensity of staining of individual cells for TLR4 was measured over a 3 hour time course of exposure to LPS (A) or MALP-2 (B). Data expressed as mean ± SE (n = 3 subjects). *P<0.05, **P<0.002, ***P<0.0001.</p
<p>Peritoneal macrophages were isolated from both WT and conditional gp96-KO and treated with lipopo...
<p>A, Western blot of total TLR4 protein expression in primary rat AM treated with LPS (100 ng/ml, 1...
<p><b>A:</b> FLSs were pretreated with TAK (5 µM) and anti-TLR4 (1 µg/mL) for 24 h and then stimulat...
<p>Alveolar macrophages (A) and ATII cells (B) were exposed to LPS (100 ng/ml) over a three hour tim...
<p>Alveolar macrophages (A) and ATII cells (B) were exposed to MALP-2 (100 ng/ml) over a three hour ...
<p>Cells were exposed to LPS (1–100 ng/ml) in the presence and absence of serum for 24 hours. Condit...
<p>Cells were exposed to MALP-2 (1–100 ng/ml) in the presence and absence of serum for 24 hours. Con...
<p>Cells were pre-incubated for 30 min with 10 µM of inhibitors of p38 (SB202190), JNK (SP600125) or...
<p>RAW 264.7 macrophages were exposed to 1 µg/mL of LPS, during 18 h and cell viability were assesse...
<p>Cells were pre-incubated for 30 min with 10 µM of inhibitors of p38 (SB202190), JNK (SP600125) or...
<p>Cells were pre-incubated with an anti-CD14 or anti-MD2 neutralising antibody for 1 hr before expo...
<p>A) Peritoneal macrophages from WT, conditional gp96-KO and Tlr4-KO mice were treated with LPS for...
<p>Under high magnification it can be seen that, in alveolar macrophages (A), there is distinct expr...
<p>Viability of LPS stimulated RAW 264.7 macrophages, after 19 h of exposure to the tested compounds...
<p>Cells were pretreated or not with malvidin for 30 min and exposed or not to LPS for 1h. Medium wa...
<p>Peritoneal macrophages were isolated from both WT and conditional gp96-KO and treated with lipopo...
<p>A, Western blot of total TLR4 protein expression in primary rat AM treated with LPS (100 ng/ml, 1...
<p><b>A:</b> FLSs were pretreated with TAK (5 µM) and anti-TLR4 (1 µg/mL) for 24 h and then stimulat...
<p>Alveolar macrophages (A) and ATII cells (B) were exposed to LPS (100 ng/ml) over a three hour tim...
<p>Alveolar macrophages (A) and ATII cells (B) were exposed to MALP-2 (100 ng/ml) over a three hour ...
<p>Cells were exposed to LPS (1–100 ng/ml) in the presence and absence of serum for 24 hours. Condit...
<p>Cells were exposed to MALP-2 (1–100 ng/ml) in the presence and absence of serum for 24 hours. Con...
<p>Cells were pre-incubated for 30 min with 10 µM of inhibitors of p38 (SB202190), JNK (SP600125) or...
<p>RAW 264.7 macrophages were exposed to 1 µg/mL of LPS, during 18 h and cell viability were assesse...
<p>Cells were pre-incubated for 30 min with 10 µM of inhibitors of p38 (SB202190), JNK (SP600125) or...
<p>Cells were pre-incubated with an anti-CD14 or anti-MD2 neutralising antibody for 1 hr before expo...
<p>A) Peritoneal macrophages from WT, conditional gp96-KO and Tlr4-KO mice were treated with LPS for...
<p>Under high magnification it can be seen that, in alveolar macrophages (A), there is distinct expr...
<p>Viability of LPS stimulated RAW 264.7 macrophages, after 19 h of exposure to the tested compounds...
<p>Cells were pretreated or not with malvidin for 30 min and exposed or not to LPS for 1h. Medium wa...
<p>Peritoneal macrophages were isolated from both WT and conditional gp96-KO and treated with lipopo...
<p>A, Western blot of total TLR4 protein expression in primary rat AM treated with LPS (100 ng/ml, 1...
<p><b>A:</b> FLSs were pretreated with TAK (5 µM) and anti-TLR4 (1 µg/mL) for 24 h and then stimulat...