Effect of human and feline ECs <i>Bartonella</i> infection on cell migration assessed in wound healing assay.

<p>A: Healing test (FSkMEC and FSkMEC-H1) Healing distance = D − d. B: Healing test (HSkMEC and HSkMEC-H1) C: Quantification of the effect of <i>Bartonella</i> infection on wound healing <i>B. henselae</i> infection increased strongly human Skin Microvascular ECs (HSkMEC) migration, in a less extent human macrovascular ECs (iHUVEC) migration but did not affect feline ECs (FOmEC and FSkMEC). Results show mean ± standard deviation from three independent experiments. (iHUVEC <i>versus</i> HSkMEC controls: ¶p = .015; infected cells <i>versus</i> uninfected cells: *p<0.05). NSI: No Significant Increase. H1: <i>B. henselae</i> human type I strain (reference strain Houston-1 ATCC 49882); H2: <i>B. henselae</i> human type II strain (Marseille); F1: <i>B. henselae</i> feline type I strain (F1 297172); F2: <i>B. henselae</i> feline type II strain; Bt: <i>B. tribocorum</i>.