Effect of <i>B. henselae</i> infection on intracellular cAMP production in human and feline EC lines.

<p><i>B. henselae</i> infection did not significantly increase cAMP production by ECs, except for iHUVEC infected by H1 strain. Results were monitored 30 h post infection with bacteria (M.O.I. of 150) and expressed in fmol/well as mean ± standard deviation (*p<0.05 for the differences between infected cells <i>versus</i> uninfected cells; #, ¶ and & p<0.05, for the differences between uninfected cells). H1: <i>B. henselae</i> human type I strain (reference strain Houston-1 ATCC 49882); F1: <i>B. henselae</i> feline type I strain (F1 297172); F2: <i>B. henselae</i> feline type II strain; Bt: <i>B. tribocorum</i>. iHUVEC: immortalized Human Umbilical Vein Endothelial Cells; HSkMEC: Human Skin Microvascular Endothelial Cells; FOmEC: Feline Umbilical Vein Endothelial Cells; FSkMEC: Feline Skin Microvascular Endothelial Cells.