Histological analysis of lymphoid follicles of MLNs of infected mice.

<p>(A) In wild type (WT) mice, section of lymphoid follicles showed scarce apoptotic bodies (arrow). In infected gal-3−/− mice (B), there was high number of cellular debris dispersed throughout the follicles (arrows). Immunofluorescence to MOMA-2+ macrophages. (C) Immunoreactivity for MOMA-2 Alexa 488 (green cells) in MLNs of WT and (D) in galectin-3−/− mice. (E) Detailed MOMA-2+ cell clusters in WT mice and (F) rare MOMA-2+ cells in the absence of galectin-3. The nuclei were stained with DAPI. Data are representative of three independent experiments, each carried out in three mice with chronic infection.