Increased histopathology in MDA5^−/− mice.

<p>A) H&E micrographs of lung sections obtained from WT and MDA5^−/− mice infected with 400K pfu SeV on d5, d9, d12 PI. B) FACS analysis of lymphocytes derived from the lungs of WT and MDA5^−/− mice, <i>uninfected (top panels) and d5 post infected (bottom panels)</i> stained with anti-CD8 and H-2K^b: FAPGNYPAL pentamer.