The influence of IFN-β treatment on EAU activity, production of IFN- γ, IL-17 and IL-10.

<p>Clinical scores (A) and histology scores on day 13(B) and day 16 (C) of IFN-β or PBS treated EAU mice. Splenocytes (D-F) and DLN cells (G-I) from day 16 with or without IFN-β treatment were activated with IRBP_161-180 (20 µg/ml) or anti-CD3 and anti-CD28 (1 µg/ml) for 72 hours. Cytokines were analyzed by ELISA. Data are representative of three independent experiments with at least five mice per group. **p<0.01, *p<0.05.