<p>A) Total CD4<sup>−</sup>CD8<sup>−</sup> cells expressed as a % of CD45RA<sup>+</sup> cells (left panel) and CD45RA<sup>−</sup> cells (right panel) in all 5 patient groups. B) Effector∶Effector memory ratios in adult patient groups for CD45RA<sup>+</sup> cells (% T<sub>TermEff</sub>/% T<sub>EMRA</sub><sup>+</sup>; left panel) and CD45RA<sup>−</sup> cells (% T<sub>EFF</sub>/% T<sub>EM</sub>; right panel). Each point represents an individual patient and the horizontal lines represent geometric means; the Mann-Whitney U test was used to derive p-values.</p
<p>Flow cytometry was used to measure the proportion of all CD4+T cells in blood (3A), ileum (3B), a...
<p>(A) Gating strategy for conventional CD4<sup>+</sup> and CD8<sup>+</sup> T cells from human perip...
<p>(A) Proportions of CD4 (upper plots) and CD8 (lower plots) T cells specific for the indicated HIV...
<p>Data for T<sub>EFF</sub> (left panels) and T<sub>EM</sub> (middle panels) cells are expressed as ...
<p>(A) Density and overlay dot plots of memory subsets in total (density) and HIV-specific CD8<sup>+...
<p>Data for CD45RA<sup>+</sup> (top panels) and CD45RA<sup>−</sup> (bottom panels) cells are express...
<p>Percentages of early-differentiated CD4+ T-cells in A (CD27+CD28+) and C (CD27+CD28+CD45RA+CD45RO...
<p>(A) Total CD8+ T-cells (grey) vs. antigen-specific CD8+ T-cells (black) belonging to the differen...
<p>*p-values determined using Mann–Whitney U-tests. Subsets of CD4<sup>+</sup> T cells are presented...
<p>(A) Gini-TCR skewing index values in naive (T<sub>Naive</sub>; CD45RA+CCR7+), central memory (T<s...
<p>(<b>A</b>) Representative flow cytometric plots of CCR7 versus CD45RO from a pre- (day -159) and ...
<p>Mean values are illustrated throughout. The black axis indicates percentages for mono-functional ...
<p>(A-B) Gating strategy for the assessment of the CD57 distribution in subsets of (A) overall CD8+ ...
<p>Proportional representation of circulating T<sub>EM</sub> (CD4<sup>+</sup>CCR7<sup>−</sup>CD45RA<...
<p>T-cell subsets were based on the CD27 and CD45RO cell surface markers. A HAT patient before and a...
<p>Flow cytometry was used to measure the proportion of all CD4+T cells in blood (3A), ileum (3B), a...
<p>(A) Gating strategy for conventional CD4<sup>+</sup> and CD8<sup>+</sup> T cells from human perip...
<p>(A) Proportions of CD4 (upper plots) and CD8 (lower plots) T cells specific for the indicated HIV...
<p>Data for T<sub>EFF</sub> (left panels) and T<sub>EM</sub> (middle panels) cells are expressed as ...
<p>(A) Density and overlay dot plots of memory subsets in total (density) and HIV-specific CD8<sup>+...
<p>Data for CD45RA<sup>+</sup> (top panels) and CD45RA<sup>−</sup> (bottom panels) cells are express...
<p>Percentages of early-differentiated CD4+ T-cells in A (CD27+CD28+) and C (CD27+CD28+CD45RA+CD45RO...
<p>(A) Total CD8+ T-cells (grey) vs. antigen-specific CD8+ T-cells (black) belonging to the differen...
<p>*p-values determined using Mann–Whitney U-tests. Subsets of CD4<sup>+</sup> T cells are presented...
<p>(A) Gini-TCR skewing index values in naive (T<sub>Naive</sub>; CD45RA+CCR7+), central memory (T<s...
<p>(<b>A</b>) Representative flow cytometric plots of CCR7 versus CD45RO from a pre- (day -159) and ...
<p>Mean values are illustrated throughout. The black axis indicates percentages for mono-functional ...
<p>(A-B) Gating strategy for the assessment of the CD57 distribution in subsets of (A) overall CD8+ ...
<p>Proportional representation of circulating T<sub>EM</sub> (CD4<sup>+</sup>CCR7<sup>−</sup>CD45RA<...
<p>T-cell subsets were based on the CD27 and CD45RO cell surface markers. A HAT patient before and a...
<p>Flow cytometry was used to measure the proportion of all CD4+T cells in blood (3A), ileum (3B), a...
<p>(A) Gating strategy for conventional CD4<sup>+</sup> and CD8<sup>+</sup> T cells from human perip...
<p>(A) Proportions of CD4 (upper plots) and CD8 (lower plots) T cells specific for the indicated HIV...