Measurement of technetium-99m incorporation in fractionated red blood cells.

<p>(A) Technetium-99m radioactivity, expressed as percentage of injected ^99mTc dose per gram (%ID/g), in fractionated blood for mice (n = 5) whose red blood cells were labeled by the direct method. Mice were either naïve or administered a single intravenous bolus dose (10 mg/kg) of the cross-species anti-VEGF antibody, B20-4.1, 24 h prior to assay. (B) Technetium-99m radioactivity, expressed as %ID/g, in fractionated blood from mice (n = 5) whose red blood cells were labeled by the indirect method. All donor mice were naïve; recipient mice were naïve or received a single intravenous bolus dose (10 mg/kg) of the cross-species anti-VEGF antibody, B20-4.1, 24 h prior to assay.