Schematic representation of sequence homology of the MG191 and MG192 genes with MgPars based on the <i>M. genitalium</i> G37 genome (GenBank accession number NC_000908).

<p>Divisions A through M indicated by dotted vertical lines represent the restriction fragments described previously <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0015660#pone.0015660-Peterson1" target="_blank">[13]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0015660#pone.0015660-Dallo1" target="_blank">[31]</a>. The four repeat regions B, EF, G and JKLM are highlighted in colors (consistent with colors used in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0015660#pone-0015660-g001" target="_blank">Fig. 1</a>). Homologous regions between MG191/MG192 and MgPars are indicated in identical colors. The hatched box represents intervening sequences that are unusually A-T rich and contain stop codons. The numbers bordering each segment of each of the MgPars refer to the nucleotide positions in the full-length MgPars as described elsewhere <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0015660#pone.0015660-IversonCabral1" target="_blank">[10]</a>. The line length in the diagrams is not always proportional to the number of nucleotides involved due to the presence of minor deletions/insertions. MgPars found in clinical strains involved in this study showed the same architecture but divergent sequences (with different coordinates for each region shown) compared to G37 MgPars.