Alignment of a portion of the six MG192 variants (as shown in ) and eight MgPar sequences identified in an -infected patient 199 and comparison with the MG192 and MgPar sequences of G37

<p><b>Copyright information:</b></p><p>Taken from ": an efficient strategy to generate genetic variation from a minimal genome"</p><p></p><p>Molecular Microbiology 2007;66(1):220-236.</p><p>Published online Jan 2007</p><p>PMCID:PMC2169797.</p><p>© 2007 Louisiana State University Health Sciences Center-New Orleans; Journal compilation © 2007 Blackwell Publishing Ltd</p> Nucleotide positions are in relation to the predicted translational start site of the full-length G37 MG192 gene. For MgPar 3 in both G37 and the patient's strain, the region preceding the sequence shown has homology to MG191 but not to MG192 (see ). Nucleotides identical to the variant sequence are highlighted in grey shading. Three possible recombination events are shown, which involve replacement of part of the MG192 sequence in variant by a segment from MgPar 2 (highlighted in green), MgPar 8 (highlighted in red) and MgPar 7 (highlighted in yellow) respectively. Double underlines C1 to C4 indicate highly conserved regions among all sequences shown. Single underlines indicate identical regions between MgPars in the patient's strain and MgPars in G37. The sequences of MG192 variants to and MgPars 1 through 9 identified from this patient's strain have been submitted to GenBank under Accession No. EF117283 to EF117288 and EF117293 to EF117301 respectively. Alignment of the entire MG192 variable regions and their homologous regions in MgPars shown in this figure is available upon request