Lymphoma cells show constitutively high glycolysis.

<p>(A) Glycolysis was measured in EL-4 lymphoma cells from continuous culture, without additional stimulation. Glycolysis in resting and stimulated T cells (as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0015425#pone-0015425-g001" target="_blank">Figure 1</a>) was measured for comparison. p<0.001, means that do not share a letter differ. (B) EL-4 cells were cultured for 24 hours with either control hamster IgG (unstimulated) or anti-CD3 plus anti-CD28 antibodies (stimulated) and glycolysis rates were measured. ns, not significantly different. Results are representative of 2 (A) or 3 (B) independent experiments.